Details, Fiction and megatomi.com
Details, Fiction and megatomi.com
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Our new Crystal clear+ tissue clearing system is the only technique that delipidates samples without any adjust in morphology and with small effect on structural integrity.
Megatome is usually a vibrating microtome designed to segment a broad variety of samples, from organoids and biopsy samples to expanded rodent brains and intact human organs. With significant blade vibrating frequency and minimized blade deflection, Megatome permits superior-throughput tissue sectioning with uniform area profile, as well as minimum tissue hurt and data loss.
Antibodies may take weeks to diffuse through only a few millimeters of tissue, which has a steep labeling gradient from surface area to core.
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SE utilizes a rotational electric subject to disperse highly electromobile molecules (such as antibodies or surfactant micelles) all over a porous sample devoid of detrimental electrically charged structures within the tissue. This allows two-4 day clearing of intact organs,
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Megatome is a novel microtome which allows for prime-precision sectioning of a variety of tissue samples – from organoids, to arrays of animal organs, to intact human brain hemispheres – with minimal tissue problems and information decline.
eFLASH is actually a rapid tissue labeling procedure that permits for uniform full-organ staining in 20 rounds of labeling.
The SmartSPIM light-weight sheet microscope gives unparalleled resolution and acquisition velocity during intact tissue volumes, while its modular layout allows you to up grade and personalize personal elements.
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SHIELD avoids the variability of hydrogel embedding and the knowledge decline from PFA preservation, protecting specimens for several rounds of processing.
Leverage the Crystal megatomi.com clear+ tissue clearing method, in conjunction with eFLASH and patented stochastic electrotransport technologies, to fast clear and label entire organs. Crucial highlights and capabilities involve:
Our novel SHIELD tissue preservation method kinds intramolecular bonds working with polyfunctional, adaptable epoxides to stabilize tissue architecture and safeguard the sample’s endogenous fluorescence, protein antigenicity and nucleic acids.